The Glacial® Skin Story


Headquartered in Silicon Valley, R2 Technologies is the world leader in CryoAesthetics®  medical devices. Our Glacial® platform for precision contact cooling of the skin has been shown to reduce inflammation and also lighten dark spots.

In 2014, Pansend Life Sciences, LLC, the life sciences segment of INNOVATE (NYSE: VATE), founded R2 together with Blossom Innovations, LLC and Massachusetts General Hospital to develop a technology based on their patented method of Cryomodulation™. In 2019, R2 brought on a strategic partner, Huadong Medicine Co., Ltd.

Since that time, R2 has conducted design, development and extensive clinical research to bring Glacial® Rx, Glacial® fx and Glacial® Spa to market along with an exciting product pipeline.

Scientific Founders

Our scientific founders and world-famous luminaries in aesthetic medicine, focus on the development, engineering, clinical research, and commercialization of groundbreaking technologies for aesthetic providers and consumers.

Image of founder R. Rox Anderson, M.D. Glacial Rx and Glacial fx

R. Rox Anderson, M.D.

Image of founder Henry H. L. Chan, M.D., PhD Glacial Rx and Glacial fx

Henry H. L. Chan, M.D., PhD

Dieter Manstein, M.D., PhD founder of Glacial Rx and Glacial fx

Dieter Manstein, M.D., PhD

Image of founder R. Rox Anderson, M.D. Glacial Rx and Glacial fx
R. Rox Anderson, M.D.
Image of founder Henry H. L. Chan, M.D., PhD Glacial Rx and Glacial fx
Henry H. L. Chan, M.D., PhD
Dieter Manstein, M.D., PhD founder of Glacial Rx and Glacial fx
Dieter Manstein, M.D., PhD
leadership Team

Our experienced leadership team is passionate about bringing Glacial® Skin to clinics and spas worldwide so everyone can experience the benefits of healthy Glacial skin.

Tim Holt
President & CEO

Tim has over 20 years of experience leading, launching, and scaling aesthetic medical device companies, including Reliant, ZELTIQ, Fraxel, and CoolSculpting.

Kerrie Jiang
Senior Vice President of Clinical, Quality, & Regulatory Affairs
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Kerrie brings over 20 years of experience in scientific development, clinical strategy, and regulatory affairs for category-defining aesthetic medical devices, including Fraxel and CoolSculpting.
Kristen Corpion
Vice President of Administration & Legal

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Kristen has 13 years of experience as a business attorney and entrepreneur, specializing in scaling operations, legal strategy, and cross-functional leadership for growing businesses.

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Casey Torrez
Vice President of Operations

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For over 20 years, Casey has led high-performing teams in sales operations, customer service, and logistics in medical aesthetics and lifesciences.

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Melia Smed
Senior Director of Sales

Melia brings strong leadership and a sales-driven mindset, focused on driving growth, strengthening partnerships, and expanding Glacial® Skin.

Nicole Hampy
Director of Strategic Relations & National Accounts

Nicole brings strong leadership and industry expertise, focused on building key relationships, strategic partnerships, and driving brand growth.

Francisco Javier Moreno Ruiz
Director of International Sales

Francisco brings global sales expertise and strategic leadership, focused on international expansion, distributor partnerships, and driving global growth.

Cristi DiBernardo
Director of Training & Partnerships

Cristi brings expertise in clinical education and partnerships, focused on developing impactful training, building key relationships, and strengthening provider success.

Jordan Abecasis
Director of Growth Engineering

Jordan brings technical expertise and business insight, focused on optimizing systems, streamlining operations, and driving business growth.

Ignacio Avila
Director of Manufacturing & Service

Nacho brings 20+ years of manufacturing leadership, focused on optimizing operations, scaling processes, and supporting R2’s continued growth.

board of directors

‍David A. Present, MD

Chairman, Founder, and General Partner, Pansend Life Sciences, LLC

Cherine Eldumiati Plumaker

Vice Chairman, Founder, and General Partner, Pansend Life Sciences, LLC

Irina Erenburg, PhD

Founder and Chief Executive Officer, Blossom Innovations, LLC

Wuming Jiang

Huadong Medicine

Seth Orlow, MD, PhD

Professor and Chair of Dermatology, NYU School of Medicine

Tim Holt, MBA

President and Chief Executive Officer, R2 Technologies, Inc.

Mark Tao

Huadong Medicine

Ken Cappell

Retired Partner PricewaterhouseCoopers LLP